The primary action of clotrimazole is against dividing and growing organisms.Ĭlotrimazole exhibits fungistatic and fungicidal activity against isolates of Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum, Microsporum canis, Candida spp., and Malassezia pachydermatis (Pityrosporum canis). Clotrimazole: Clotrimazole is a broad-spectrum antifungal agent that is used for the treatment of dermal infections caused by various species of pathogenic dermatophytes and yeasts.Once absorbed through the skin, topical corticosteroids are handled through pharmacokinetic pathways similar to systemically administered corticosteroids.
Inflammation can increase percutaneous absorption. Topical corticosteroids can be absorbed from normal, intact skin. Betamethasone valerate, the 17-valerate ester of betamethasone, has been shown to provide anti-inflammatory and anti-pruritic activity in the topical management of corticosteroid-responsive otitis externa. Betamethasone, an analog of prednisolone, has a high degree of corticosteroid activity and a slight degree of mineralocorticosteroid activity. Betamethasone: Betamethasone valerate is a synthetic adrenocorticoid for dermatologic use.Specifically, gentamicin is active against the following organisms commonly isolated from canine ears: Staphylococcus aureus, other Staphylococcus spp., Pseudomonas aeruginosa, Proteus spp., and Escherichia coli. Gentamicin is bactericidal and acts by inhibiting normal protein synthesis in susceptible microorganisms. Gentamicin: Gentamicin sulfate is an aminoglycoside antibiotic active against a wide variety of pathogenic gram-negative and gram-positive bacteria.Otomax reduces discomfort, redness, swelling, exudate, and odor, and exerts a strong antimicrobial effect. By virtue of it's three components - Gentamicin-Betamethasone-Clotrimazole - Otomox has antibacterial, anti-inflammatory, and antifungal activity. Otomax Ointment Antimicrobial - Anti-Inflammatory Otomax Ointment For Dogs is indicated for the treatment of canine acute and chronic otitis externa associated with yeast (Malassezia pachydermatis) and/or bacteria susceptible to gentamicin.